| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50515564 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1861558 (CHEMBL4362414) |
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| Ki | 0.800000±n/a nM |
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| Citation |  Tanini, D; Ricci, L; Capperucci, A; Di Cesare Mannelli, L; Ghelardini, C; Peat, TS; Carta, F; Angeli, A; Supuran, CT Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity. Eur J Med Chem181:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50515564 |
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| n/a |
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| Name | BDBM50515564 |
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| Synonyms: | CHEMBL4535469 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24N2O8S2Te |
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| Mol. Mass. | 588.1 |
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| SMILES | [#7]S(=O)(=O)c1ccc(-[#8]-[#6]-[#6](-[#8])-[#6][Te;v2][#6]-[#6](-[#8])-[#6]-[#8]-c2ccc(cc2)S([#7])(=O)=O)cc1 |
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| Structure | 
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