| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
|---|
| Ligand | BDBM50071640 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_99856 |
|---|
| IC50 | 1±n/a nM |
|---|
| Citation |  Brown, MF; Marfat, A; Antognoli, G; Chambers, RJ; Cheng, JB; Damon, DB; Liston, TE; McGlynn, MA; O'Sullivan, SP; Owens, BS; Pillar, JS; Shirley, JT; Watson, JW N-carbamoyl analogs of Zafirlukast: potent receptor antagonists of leukotriene D4. Bioorg Med Chem Lett8:2451-6 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cysteinyl leukotriene receptor 1 |
|---|
| Name: | Cysteinyl leukotriene receptor 1 |
|---|
| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 39007.58 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
|---|
| Residue: | 340 |
|---|
| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
|
|
|
|---|
| BDBM50071640 |
|---|
| n/a |
|---|
| Name | BDBM50071640 |
|---|
| Synonyms: | CHEMBL1048 | N-Dealkylated Derivative | {3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-benzyl]-1H-indol-5-yl}-carbamic acid cyclopentyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H31N3O6S |
|---|
| Mol. Mass. | 561.649 |
|---|
| SMILES | COc1cc(ccc1Cc1c[nH]c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C |
|---|
| Structure | 
|
|---|
Search and Browse
