Reaction Details | |||
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Target | Cytochrome P450 2C9 | ||
Ligand | BDBM50517935 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1870100 (CHEMBL4371267) | ||
EC50 | 34000±n/a nM | ||
Citation | Hanson, AM; Perera, KLIS; Kim, J; Pandey, RK; Sweeney, N; Lu, X; Imhoff, A; Mackinnon, AC; Wargolet, AJ; Van Hart, RM; Frick, KM; Donaldson, WA; Sem, DS A-C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions. J Med Chem61:4720-4738 (2018) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cytochrome P450 2C9 | |||
Name: | Cytochrome P450 2C9 | ||
Synonyms: | (R)-limonene 6-monooxygenase | (S)-limonene 6-monooxygenase | CP2C9_HUMAN | CYP2C10 | CYP2C9 | CYPIIC9 | Cytochrome P450 2C9 (CYP2C9 ) | Cytochrome P450 2C9 (CYP2C9) | P-450MP | P450 MP-4/MP-8 | P450 PB-1 | S-mephenytoin 4-hydroxylase | ||
Type: | Enzyme | ||
Mol. Mass.: | 55636.33 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P11712 | ||
Residue: | 490 | ||
Sequence: |
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BDBM50517935 | |||
n/a | |||
Name | BDBM50517935 | ||
Synonyms: | CHEMBL4526434 | ||
Type | Small organic molecule | ||
Emp. Form. | C13H18O2 | ||
Mol. Mass. | 206.2808 | ||
SMILES | OC[C@H]1CC[C@@H](CC1)c1ccc(O)cc1 |r,wU:5.8,wD:2.1,(30.01,-26.44,;29.24,-27.77,;27.7,-27.77,;26.93,-26.43,;25.39,-26.43,;24.62,-27.76,;25.39,-29.1,;26.93,-29.1,;23.08,-27.76,;22.32,-26.42,;20.78,-26.42,;20.01,-27.76,;18.47,-27.76,;20.79,-29.09,;22.32,-29.09,)| | ||
Structure |