| Reaction Details |
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 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
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| Ligand | BDBM50072682 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_216272 (CHEMBL819879) |
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| IC50 | 200±n/a nM |
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| Citation |  Wischnat, R; Martin, R; Takayama, S; Wong, CH Chemoenzymatic synthesis of iminocyclitol derivatives: a useful library strategy for the development of selective fucosyltransfer enzymes inhibitors. Bioorg Med Chem Lett8:3353-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tissue alpha-L-fucosidase |
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| Name: | Tissue alpha-L-fucosidase |
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| Synonyms: | Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53690.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_34088 |
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| Residue: | 466 |
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| Sequence: | MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGV
FIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEW
ADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYG
LYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYW
NSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSID
KFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGK
WLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTK
ITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
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| BDBM50072682 |
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| n/a |
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| Name | BDBM50072682 |
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| Synonyms: | CHEMBL115930 | {[(3,4,5-Trihydroxy-2-hydroxymethyl-6-methyl-piperidin-2-ylmethyl)-carbamoyl]-methyl}-carbamic acid benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C18H27N3O7 |
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| Mol. Mass. | 397.4229 |
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| SMILES | CC1NC(CO)(CNC(=O)CNC(=O)OCc2ccccc2)C(O)C(O)C1O |
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| Structure | 
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