| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1 |
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| Ligand | BDBM50072996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_99840 (CHEMBL706759) |
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| Ki | 9.5±n/a nM |
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| Citation |  Greenspan, PD; Fujimoto, RA; Marshall, PJ; Raychaudhuri, A; Lipson, KE; Zhou, H; Doti, RA; Coppa, DE; Zhu, L; Pelletier, R; Uziel-Fusi, S; Jackson, RH; Chin, MH; Kotyuk, BL; Fitt, JJ Carboxy-substituted cinnamides: a novel series of potent, orally active LTB4 receptor antagonists. J Med Chem42:164-72 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene B4 receptor 1 |
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| Name: | Leukotriene B4 receptor 1 |
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| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37582.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15722 |
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| Residue: | 352 |
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| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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| BDBM50072996 |
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| n/a |
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| Name | BDBM50072996 |
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| Synonyms: | 3-[5-((E)-2-Diethylcarbamoyl-1-methyl-vinyl)-2-(1-phenyl-ethoxy)-phenyl]-propionic acid | CHEMBL49866 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31NO4 |
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| Mol. Mass. | 409.5179 |
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| SMILES | CCN(CC)C(=O)\C=C(/C)c1ccc(OC(C)c2ccccc2)c(CCC(O)=O)c1 |
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| Structure | 
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