| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2, membrane associated |
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| Ligand | BDBM50073197 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_156376 |
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| IC50 | 31300±n/a nM |
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| Citation |  Iwama, S; Segawa, M; Fujii, S; Ikeda, K; Katsumura, S Design and synthesis of new secretory phospholipase A2 inhibitor of a phospholipid analog. Bioorg Med Chem Lett8:3495-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2, membrane associated |
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| Name: | Phospholipase A2, membrane associated |
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| Synonyms: | GIIC sPLA2 | Group IIA phospholipase A2 | NPS-PLA2 | Non-Pancreatic Secretory Phospholipase A2 | Non-pancreatic secretory phospholipase A2 (hnps-PLA2) | PA2GA_HUMAN | PLA2B | PLA2G2A | PLA2L | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 group IIA | RASF-A |
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| Type: | Hydrolase |
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| Mol. Mass.: | 16101.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The human nps PLA2 was cloned, and expressed in E. coli. There was a refolding process in the purification. |
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| Residue: | 144 |
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| Sequence: | MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT
DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR
NKTTYNKKYQYYSNKHCRGSTPRC
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| BDBM50073197 |
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| n/a |
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| Name | BDBM50073197 |
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| Synonyms: | CHEMBL116362 | {2-[((R)-3-Dodecanoyl-2-oxo-oxazolidin-4-ylmethoxy)-hydroxy-phosphoryloxy]-ethyl}-trimethyl-ammonium |
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| Type | Small organic molecule |
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| Emp. Form. | C21H41N2O7P |
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| Mol. Mass. | 464.5332 |
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| SMILES | CCCCCCCCCCCC(=O)N1[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC1=O |
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| Structure | 
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