Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50073263 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_157700 |
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Ki | 0.120000±n/a nM |
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Citation | Randad, RS; Lubkowska, L; Eissenstat, MA; Gulnik, SV; Yu, B; Bhat, TN; Clanton, DJ; House, T; Stinson, SF; Erickson, JW Unsymmetric nonpeptidic HIV protease inhibitors containing anthranilamide as a P2' ligand. Bioorg Med Chem Lett8:3537-42 (1999) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50073263 |
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n/a |
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Name | BDBM50073263 |
Synonyms: | CHEMBL117629 | {2-[(1S,3S,4S)-4-(3-Amino-2-methyl-benzoylamino)-1-benzyl-3-hydroxy-5-phenyl-pentylcarbamoyl]-phenyl}-carbamic acid pyridin-2-ylmethyl ester |
Type | Small organic molecule |
Emp. Form. | C40H41N5O5 |
Mol. Mass. | 671.784 |
SMILES | Cc1c(N)cccc1C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)OCc1ccccn1 |
Structure |
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