Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50073353 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_157552 |
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Ki | 17±n/a nM |
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Citation | Salituro, FG; Baker, CT; Court, JJ; Deininger, DD; Kim, EE; Li, B; Novak, PM; Rao, BG; Pazhanisamy, S; Porter, MD; Schairer, WC; Tung, RD Design and synthesis of novel conformationally restricted HIV protease inhibitors. Bioorg Med Chem Lett8:3637-42 (1999) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50073353 |
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n/a |
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Name | BDBM50073353 |
Synonyms: | CHEMBL332611 | {(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfonyl)-amino]-2-hydroxy-propyl}-phenethyl-carbamic acid pyridin-3-ylmethyl ester |
Type | Small organic molecule |
Emp. Form. | C31H39N3O6S |
Mol. Mass. | 581.723 |
SMILES | COc1ccc(cc1)S(=O)(=O)N(C[C@@H](O)CN(CCc1ccccc1)C(=O)OCc1cccnc1)CC1CCCC1 |
Structure |
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