| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein |
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| Ligand | BDBM50075160 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_161074 |
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| IC50 | 140±n/a nM |
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| Citation |  Jarvest, RL; Pinto, IL; Ashman, SM; Dabrowski, CE; Fernandez, AV; Jennings, LJ; Lavery, P; Tew, DG Inhibition of herpes proteases and antiviral activity of 2-substituted thieno[2,3-d]oxazinones. Bioorg Med Chem Lett9:443-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein |
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| Name: | Genome polyprotein |
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| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44361.04 |
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| Organism: | Human rhinovirus B |
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| Description: | ChEMBL_158953 |
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| Residue: | 401 |
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| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
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| BDBM50075160 |
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| n/a |
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| Name | BDBM50075160 |
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| Synonyms: | (Z)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-yl)-ethyl]-3-phenyl-3-phenylsulfanyl-acrylamide | CHEMBL422823 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20N2O3S2 |
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| Mol. Mass. | 448.557 |
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| SMILES | C[C@H](NC(=O)\C=C(/Sc1ccccc1)c1ccccc1)c1nc2scc(C)c2c(=O)o1 |
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| Structure | 
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