| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
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| Ligand | BDBM50075276 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_200682 |
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| Ki | 5.9±n/a nM |
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| Citation |  Pasternak, A; Pan, Y; Marino, D; Sanderson, PE; Mosley, R; Rohrer, SP; Birzin, ET; Huskey, SE; Jacks, T; Schleim, KD; Cheng, K; Schaeffer, JM; Patchett, AA; Yang, L Potent, orally bioavailable somatostatin agonists: good absorption achieved by urea backbone cyclization. Bioorg Med Chem Lett9:491-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 2 |
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| Name: | Somatostatin receptor type 2 |
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| Synonyms: | SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41344.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30874 |
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| Residue: | 369 |
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| Sequence: | MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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| BDBM50075276 |
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| n/a |
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| Name | BDBM50075276 |
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| Synonyms: | (R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-3-(3-phenyl-butyl)-imidazolidin-1-yl]-butyrylamino}-hexanoic acid tert-butyl ester | CHEMBL147214 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H49N5O4 |
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| Mol. Mass. | 603.7947 |
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| SMILES | CC(CCN1CCN([C@H]([C@@H](C)c2c[nH]c3ccccc23)C(=O)N[C@H](CCCCN)C(=O)OC(C)(C)C)C1=O)c1ccccc1 |
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| Structure | 
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