| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
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| Ligand | BDBM50075289 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_200690 |
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| Ki | 10±n/a nM |
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| Citation |  Pasternak, A; Pan, Y; Marino, D; Sanderson, PE; Mosley, R; Rohrer, SP; Birzin, ET; Huskey, SE; Jacks, T; Schleim, KD; Cheng, K; Schaeffer, JM; Patchett, AA; Yang, L Potent, orally bioavailable somatostatin agonists: good absorption achieved by urea backbone cyclization. Bioorg Med Chem Lett9:491-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 2 |
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| Name: | Somatostatin receptor type 2 |
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| Synonyms: | SOMATOSTATIN SST2 | SSR2_MOUSE | Smstr2 | Somatostatin receptor | Somatostatin receptor 2 | Somatostatin receptor type 2 | Sst2 | Sstr2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41234.26 |
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| Organism: | MOUSE |
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| Description: | SOMATOSTATIN SST2 SSTR2 MOUSE::P30875 |
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| Residue: | 369 |
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| Sequence: | MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVIL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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| BDBM50075289 |
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| n/a |
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| Name | BDBM50075289 |
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| Synonyms: | 1-[5-amino-1-methyloxycarbonyl-(1R)-pentylcarbamoyl]-2-(1H-3-indolyl)-(1R)-ethyl spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1'-carboxylate | CHEMBL146022 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H40N4O5 |
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| Mol. Mass. | 560.6838 |
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| SMILES | COC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)OC(=O)N1CCC2(CCc3ccccc23)CC1 |
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| Structure | 
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