| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor receptor 2 |
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| Ligand | BDBM50403726 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_51277 |
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| Ki | 20±n/a nM |
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| Citation |  Luthin, DR; Rabinovich, AK; Bhumralkar, DR; Youngblood, KL; Bychowski, RA; Dhanoa, DS; May, JM Synthesis and biological activity of oxo-7H-benzo[e]perimidine-4-carboxylic acid derivatives as potent, nonpeptide corticotropin releasing factor (CRF) receptor antagonists. Bioorg Med Chem Lett9:765-70 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Corticotropin-releasing factor receptor 2 |
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| Name: | Corticotropin-releasing factor receptor 2 |
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| Synonyms: | CRF-R-2 | CRF-R2 | CRF-RB | CRFR-2 | CRFR2_MOUSE | CRH-R-2 | CRH-R2 | Corticotropin releasing factor receptor 2 | Corticotropin-releasing factor receptor 2 | Corticotropin-releasing hormone receptor 2 | Crf2r | Crhr2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47628.12 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_51276 |
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| Residue: | 411 |
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| Sequence: | MDAALLLSLLEANCSLALAEELLLDGWGVPPDPEGPYTYCNTTLDQIGTCWPQSAPGALV
ERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIVN
YLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNIAWFLLQLIDHEVHEGN
EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIII
AWAVGKLYYENEQCWFGKEAGDLVDYIYQGPVMLVLLINFVFLFNIVRILMTKLRASTTS
ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYC
FFNGEVRAALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
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| BDBM50403726 |
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| n/a |
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| Name | BDBM50403726 |
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| Synonyms: | CHEMBL2112936 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H30N6O2 |
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| Mol. Mass. | 482.5768 |
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| SMILES | N[C@H]1CCCC[C@@H]1NC(=O)c1c2N[C@@H]3CCCC[C@H]3Nc2c2C(=O)c3ccccc3-c3ncnc1c23 |
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| Structure | 
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