| Reaction Details |
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 | Report a problem with these data |
| Target | Large neutral amino acids transporter small subunit 1 |
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| Ligand | BDBM18073 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1885219 (CHEMBL4386801) |
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| IC50 | 69000±n/a nM |
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| Citation |  Hall, C; Wolfe, H; Wells, A; Chien, HC; Colas, C; Schlessinger, A; Giacomini, KM; Thomas, AA l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan. Bioorg Med Chem Lett29:2254-2258 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Large neutral amino acids transporter small subunit 1 |
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| Name: | Large neutral amino acids transporter small subunit 1 |
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| Synonyms: | 4F2 LC | 4F2 light chain | 4F2LC | CD98 light chain | CD98LC | CD98LC | Integral membrane protein E16 | L-type amino acid transporter 1 | LAT1 | LAT1_HUMAN | Large neutral amino acids transporter small subunit 1 | MPE16 | SLC7A5 | Solute carrier family 7 member 5 | hLAT1 | y+ system cationic amino acid transporter |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55013.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_100160 |
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| Residue: | 507 |
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| Sequence: | MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV
GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM
LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL
LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL
STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP
SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH
RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
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| BDBM18073 |
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| n/a |
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| Name | BDBM18073 |
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| Synonyms: | (2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523 | L-[2,3,4,5,6-3H]phenylalanine | L-phenylalanine | Phenylalanine | US11021454, Compound L-phe |
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| Type | Amino Acid |
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| Emp. Form. | C9H11NO2 |
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| Mol. Mass. | 165.1891 |
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| SMILES | N[C@@H](Cc1ccccc1)C(O)=O |
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| Structure | 
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