| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50403784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1888741 (CHEMBL4390418) |
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| Ki | 251±n/a nM |
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| Citation |  Zar?ba, P; Ja?kowska, J; Czekaj, I; Sata?a, G Design, synthesis and molecular modelling of new bulky Fananserin derivatives with altered pharmacological profile as potential antidepressants. Bioorg Med Chem27:3396-3407 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50403784 |
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| n/a |
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| Name | BDBM50403784 |
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| Synonyms: | CHEMBL430280 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31N3O3S |
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| Mol. Mass. | 465.608 |
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| SMILES | COc1ccccc1N1CCN(CCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 |
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| Structure | 
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