| Reaction Details |
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 | Report a problem with these data |
| Target | Collagenase 3 |
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| Ligand | BDBM50078668 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_101902 |
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| IC50 | 0.400000±n/a nM |
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| Citation |  Freskos, JN; McDonald, JJ; Mischke, BV; Mullins, PB; Shieh, HS; Stegeman, RA; Stevens, AM Synthesis and identification of conformationally constrained selective MMP inhibitors. Bioorg Med Chem Lett9:1757-60 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Collagenase 3 |
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| Name: | Collagenase 3 |
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| Synonyms: | MMP-13 | MMP13 | MMP13_HUMAN | Matrix metalloproteinase-13 | Matrix metalloproteinase-13 (MMP-13) | Matrix metalloproteinase-13 (MMP13) |
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| Type: | Enzyme |
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| Mol. Mass.: | 53808.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P45452 |
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| Residue: | 471 |
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| Sequence: | MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENA
ASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTY
RIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDG
PSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALM
FPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGET
MIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGY
DILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLI
EEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
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| BDBM50078668 |
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| n/a |
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| Name | BDBM50078668 |
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| Synonyms: | 3-(4-Phenylsulfanyl-benzenesulfonyl)-cyclohexanethiol | CHEMBL300697 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20O2S3 |
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| Mol. Mass. | 364.545 |
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| SMILES | SC1CCCC(C1)S(=O)(=O)c1ccc(Sc2ccccc2)cc1 |
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| Structure | 
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