| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Stromelysin-3 |
|---|
| Ligand | BDBM50078938 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106454 (CHEMBL716816) |
|---|
| Ki | 5±n/a nM |
|---|
| Citation |  Vassiliou, S; Mucha, A; Cuniasse, P; Georgiadis, D; Lucet-Levannier, K; Beau, F; Kannan, R; Murphy, G; Knäuper, V; Rio, MC; Basset, P; Yiotakis, A; Dive, V Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: a structure-activity study. J Med Chem42:2610-20 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Stromelysin-3 |
|---|
| Name: | Stromelysin-3 |
|---|
| Synonyms: | MMP11_MOUSE | Matrix metalloproteinase 11 | Mmp11 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 55452.62 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_106453 |
|---|
| Residue: | 492 |
|---|
| Sequence: | MARAACLLRAISRVLLLPLPLLLLLLLLLPSPLMARARPPESHRHHPVKKGPRLLHAALP
NTLTSVPASHWVPSPAGSSRPLRCGVPDLPDVLNARNRQKRFVLSGGRWEKTDLTYRILR
FPWQLVREQVRQTVAEALQVWSEVTPLTFTEVHEGRADIMIDFARYWHGDNLPFDGPGGI
LAHAFFPKTHREGDVHFDYDETWTIGDNQGTDLLQVAAHEFGHVLGLQHTTAAKALMSPF
YTFRYPLSLSPDDRRGIQHLYGRPQMAPTSPAPTLSSQAGTDTNEIALLEPETPPDVCET
SFDAVSTIRGELFFFKAGFVWRLRSGRLQPGYPALASRHWQGLPSPVDAAFEDAQGQIWF
FQGAQYWVYDGEKPVLGPAPLSKLGLQGSPVHAALVWGPEKNKIYFFRGGDYWRFHPRTQ
RVDNPVPRRSTDWRGVPSEIDAAFQDAEGYAYFLRGHLYWKFDPVKVKVLEGFPRPVGPD
FFDCAEPANTFR
|
|
|
|---|
| BDBM50078938 |
|---|
| n/a |
|---|
| Name | BDBM50078938 |
|---|
| Synonyms: | (2-{N-[1-Carbamoyl-2-(1H-indol-3-yl)-ethyl]-hydrazinocarbonyl}-5-phenyl-pentyl)-{1-[(6,8-dichloro-2-oxo-2H-chromene-3-carbonyl)-amino]-2-phenyl-ethyl}-phosphinic acid | CHEMBL315046 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C41H40Cl2N5O7P |
|---|
| Mol. Mass. | 816.665 |
|---|
| SMILES | NN(C(Cc1c[nH]c2ccccc12)C(N)=O)C(=O)C(CCCc1ccccc1)CP(O)(=O)C(Cc1ccccc1)NC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O |
|---|
| Structure | 
|
|---|
Search and Browse
