Reaction Details |
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Target | 5-hydroxytryptamine receptor 1B |
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Ligand | BDBM50079939 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1394 (CHEMBL832874) |
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Ki | >1000±n/a nM |
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Citation | Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents. J Med Chem42:3342-55 (1999) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 1B |
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Name: | 5-hydroxytryptamine receptor 1B |
Synonyms: | 5HT1B_PIG | HTR1B | Serotonin 1b (5-HT1b) receptor |
Type: | PROTEIN |
Mol. Mass.: | 16950.74 |
Organism: | Sus scrofa |
Description: | ChEMBL_1394 |
Residue: | 150 |
Sequence: | VEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRAPDLPSESGSPVYVNQVKV
RVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLAMPICKDACWFHLAIFD
FFTWLGYLNSLINPIIYTMFNEDFKQAFHK
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BDBM50079939 |
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n/a |
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Name | BDBM50079939 |
Synonyms: | (7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2-methoxy-phenyl)-piperidin-4-ylmethyl]-amine | CHEMBL418854 |
Type | Small organic molecule |
Emp. Form. | C22H27ClN2O3 |
Mol. Mass. | 402.914 |
SMILES | COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 |
Structure |
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