| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50080056 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58760 (CHEMBL669148) |
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| Ki | 1010±n/a nM |
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| Citation |  Höök, BB; Brege, C; Linnanen, T; Mikaels, A; Malmberg, A; Johansson, AM Derivatives of (R)-2-amino-5-methoxytetralin: antagonists and inverse agonists at the dopamine D2A receptor. Bioorg Med Chem Lett9:2167-72 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50080056 |
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| n/a |
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| Name | BDBM50080056 |
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| Synonyms: | Benzyl-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine | CHEMBL65896 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21NO |
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| Mol. Mass. | 267.3654 |
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| SMILES | COc1cccc2C[C@@H](CCc12)NCc1ccccc1 |
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| Structure | 
|
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