| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 1 group I member 3 |
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| Ligand | BDBM50030476 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1897372 (CHEMBL4399407) |
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| EC50 | 620±n/a nM |
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| Citation |  Liang, D; Li, L; Lynch, C; Diethelm-Varela, B; Xia, M; Xue, F; Wang, H DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor. ACS Med Chem Lett10:1039-1044 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 1 group I member 3 |
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| Name: | Nuclear receptor subfamily 1 group I member 3 |
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| Synonyms: | CAR | NR1I3 | NR1I3_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39953.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1434936 |
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| Residue: | 352 |
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| Sequence: | MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
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| BDBM50030476 |
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| n/a |
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| Name | BDBM50030476 |
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| Synonyms: | CHEMBL458603 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H12Cl3N3OS |
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| Mol. Mass. | 436.742 |
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| SMILES | Clc1ccc(cc1)-c1nc2sccn2c1\C=N\OCc1ccc(Cl)c(Cl)c1 |
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| Structure | 
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