Reaction Details |
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Target | Thromboxane A2 receptor |
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Ligand | BDBM50081439 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_158475 |
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Ki | 2100±n/a nM |
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Citation | Ruel, R; Lacombe, P; Abramovitz, M; Godbout, C; Lamontagne, S; Rochette, C; Sawyer, N; Stocco, R; Tremblay, NM; Metters, KM; Labelle, M New class of biphenylene dibenzazocinones as potent ligands for the human EP1 prostanoid receptor. Bioorg Med Chem Lett9:2699-704 (1999) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Thromboxane A2 receptor |
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Name: | Thromboxane A2 receptor |
Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
Type: | Enyzme |
Mol. Mass.: | 37445.28 |
Organism: | Homo sapiens (Human) |
Description: | P21731 |
Residue: | 343 |
Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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BDBM50081439 |
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n/a |
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Name | BDBM50081439 |
Synonyms: | CHEMBL92539 | sulfonylurea analogue |
Type | Small organic molecule |
Emp. Form. | C38H35N3O4S |
Mol. Mass. | 629.767 |
SMILES | CN(CCc1ccccc1)C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 |
Structure |
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