| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoylglutathione lyase |
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| Ligand | BDBM50526943 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1901791 (CHEMBL4404013) |
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| Ki | 1.000000±n/a nM |
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| Citation |  Jin, T; Zhao, L; Wang, HP; Huang, ML; Yue, Y; Lu, C; Zheng, ZB Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoylglutathione lyase |
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| Name: | Lactoylglutathione lyase |
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| Synonyms: | Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase |
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| Type: | Enzyme |
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| Mol. Mass.: | 20772.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q04760 |
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| Residue: | 184 |
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| Sequence: | MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQK
CDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKM
ATLM
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| BDBM50526943 |
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| n/a |
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| Name | BDBM50526943 |
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| Synonyms: | CHEMBL4436073 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N4O8 |
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| Mol. Mass. | 448.4266 |
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| SMILES | N[C@@H](CCC(=O)N[C@@H](CCC(=O)N(O)c1cccc(c1)C#C)C(=O)NCC(O)=O)C(O)=O |r| |
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| Structure | 
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