| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lactoylglutathione lyase |
|---|
| Ligand | BDBM50526947 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1901787 (CHEMBL4404009) |
|---|
| Ki | 150±n/a nM |
|---|
| Citation |  Jin, T; Zhao, L; Wang, HP; Huang, ML; Yue, Y; Lu, C; Zheng, ZB Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem28:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lactoylglutathione lyase |
|---|
| Name: | Lactoylglutathione lyase |
|---|
| Synonyms: | 4.4.1.5 | Aldoketomutase | Glo1 | Glx I | Glyoxalase I | Ketone-aldehyde mutase | LGUL_MOUSE | Lactoylglutathione lyase | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 20805.83 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_10270 |
|---|
| Residue: | 184 |
|---|
| Sequence: | MAEPQPASSGLTDETAFSCCSDPDPSTKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQK
LDFPAMKFSLYFLAYEDKNDIPKDKSEKTAWTFSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKI
ATII
|
|
|
|---|
| BDBM50526947 |
|---|
| n/a |
|---|
| Name | BDBM50526947 |
|---|
| Synonyms: | CHEMBL4584432 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H14O6 |
|---|
| Mol. Mass. | 290.2681 |
|---|
| SMILES | Cc1cc(O)c(O)c(Oc2cc(C)c(C(O)=O)c(O)c2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
