| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-dependent Clp protease proteolytic subunit |
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| Ligand | BDBM50527100 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1902063 (CHEMBL4404285) |
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| IC50 | 1500±n/a nM |
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| Citation |  Ju, Y; He, L; Zhou, Y; Yang, T; Sun, K; Song, R; Yang, Y; Li, C; Sang, Z; Bao, R; Luo, Y Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers J Med Chem63:3104-3119 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| ATP-dependent Clp protease proteolytic subunit |
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| Name: | ATP-dependent Clp protease proteolytic subunit |
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| Synonyms: | CLPP_STAA8 | Endopeptidase Clp | clpP |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21508.79 |
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| Organism: | Staphylococcus aureus (strain NCTC 8325) |
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| Description: | ChEMBL_796596 |
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| Residue: | 195 |
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| Sequence: | MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDI
YLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEV
MIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEA
KEYGLIDEVMVPETK
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| BDBM50527100 |
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| n/a |
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| Name | BDBM50527100 |
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| Synonyms: | CHEMBL4457363 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31BN2O5 |
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| Mol. Mass. | 426.314 |
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| SMILES | COc1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)B(O)O)c(C)c1 |r| |
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| Structure | 
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