| Reaction Details |
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 | Report a problem with these data |
| Target | Retinal dehydrogenase 2 |
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| Ligand | BDBM50527781 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1903540 (CHEMBL4405762) |
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| IC50 | 54600±n/a nM |
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| Citation |  Quattrini, L; Gelardi, ELM; Coviello, V; Sartini, S; Ferraris, DM; Mori, M; Nakano, I; Garavaglia, S; La Motta, C Imidazo[1,2- J Med Chem63:4603-4616 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinal dehydrogenase 2 |
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| Name: | Retinal dehydrogenase 2 |
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| Synonyms: | AL1A2_HUMAN | ALDH1A2 | Aldehyde dehydrogenase family 1 member A2 | RALDH 2 | RALDH(II) | RALDH2 | Retinal dehydrogenase 2 | Retinaldehyde-specific dehydrogenase type 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56720.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109700 |
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| Residue: | 518 |
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| Sequence: | MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNP
ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVL
ATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC
GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILP
GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD
LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG
PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG
PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ
SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
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| BDBM50527781 |
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| n/a |
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| Name | BDBM50527781 |
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| Synonyms: | CHEMBL4456676 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H14N2 |
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| Mol. Mass. | 270.3279 |
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| SMILES | c1c(nc2ccc(cn12)-c1ccccc1)-c1ccccc1 |
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| Structure | 
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