| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Discoidin domain-containing receptor 2 |
|---|
| Ligand | BDBM50528541 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1905312 (CHEMBL4407670) |
|---|
| IC50 | 933±n/a nM |
|---|
| Citation |  Zhu, D; Huang, H; Pinkas, DM; Luo, J; Ganguly, D; Fox, AE; Arner, E; Xiang, Q; Tu, ZC; Bullock, AN; Brekken, RA; Ding, K; Lu, X 2-Amino-2,3-dihydro-1 J Med Chem62:7431-7444 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Discoidin domain-containing receptor 2 |
|---|
| Name: | Discoidin domain-containing receptor 2 |
|---|
| Synonyms: | DDR2 | DDR2_HUMAN | Discoidin domain receptor 2 (DDR2) | Discoidin domain-containing receptor 2 | Discoidin domain-containing receptor 2 (DDR2) | Epithelial discoidin domain-containing receptor 2 (DDR2) | NTRKR3 | TKT | TYRO10 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 96717.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q16832 |
|---|
| Residue: | 855 |
|---|
| Sequence: | MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
SFQEIHLLLLQQGDE
|
|
|
|---|
| BDBM50528541 |
|---|
| n/a |
|---|
| Name | BDBM50528541 |
|---|
| Synonyms: | CHEMBL4437631 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H23F3N6O |
|---|
| Mol. Mass. | 492.4956 |
|---|
| SMILES | CN([C@@H]1Cc2ccc(cc2C1)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1cnc(C)c1)c1cncnc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
