| Reaction Details |
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 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 2 |
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| Ligand | BDBM50528780 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1906199 (CHEMBL4408557) |
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| IC50 | 590±n/a nM |
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| Citation |  Du, Q; Feng, X; Wang, Y; Xu, X; Zhang, Y; Qu, X; Li, Z; Bian, J Discovery of phosphonamidate IDO1 inhibitors for the treatment of non-small cell lung cancer. Eur J Med Chem182:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Indoleamine 2,3-dioxygenase 2 |
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| Name: | Indoleamine 2,3-dioxygenase 2 |
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| Synonyms: | I23O2_HUMAN | IDO-2 | IDO2 | INDOL1 | Indoleamine 2,3-dioxygenase-like protein 1 | Indoleamine-pyrrole 2,3-dioxygenase-like protein 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47079.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109909 |
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| Residue: | 420 |
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| Sequence: | MLHFHYYDTSNKIMEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIA
NKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVL
PRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGF
ILVTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDP
DIFYAGIRIFLSGWKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSK
ESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYH
ITMVTKYLITAAAKAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG
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| BDBM50528780 |
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| n/a |
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| Name | BDBM50528780 |
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| Synonyms: | CHEMBL4436582 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21BrFN6O4P |
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| Mol. Mass. | 479.241 |
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| SMILES | COP(C)(=O)NCCCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O |
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| Structure | 
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