| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type 1G |
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| Ligand | BDBM50529754 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1909769 (CHEMBL4412215) |
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| IC50 | 4810±n/a nM |
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| Citation |  Mularski, J; Malarz, K; Pacholczyk, M; Musiol, R The p53 stabilizing agent CP-31398 and multi-kinase inhibitors. Designing, synthesizing and screening of styrylquinazoline series. Eur J Med Chem163:610-625 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type 1G |
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| Name: | Calcium/calmodulin-dependent protein kinase type 1G |
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| Synonyms: | CAMK1G | CLICK3 | CaM kinase I gamma | KCC1G_HUMAN | VWS1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53096.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774599 |
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| Residue: | 476 |
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| Sequence: | MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAF
RDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDA
SLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTAC
GTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFES
PFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFA
KSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSRPSSPEITITEAPV
LDHSVALPALTQLPCQHGRRPTAPGGRSLNCLVNGSLHISSSLVPMHQGSLAAGPCGCCS
SCLNIGSKGKSSYCSEPTLLKKANKKQNFKSEVMVPVKASGSSHCRAGQTGVCLIM
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| BDBM50529754 |
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| n/a |
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| Name | BDBM50529754 |
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| Synonyms: | CHEMBL579353 | GNF-Pf-2789 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34Cl2N4O2 |
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| Mol. Mass. | 517.49 |
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| SMILES | CCN(CC)CCCC(C)Nc1nc(\C=C\c2cc(OC)c(OC)cc2Cl)nc2cc(Cl)ccc12 |
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| Structure | 
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