| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50451122 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_147330 |
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| IC50 | 571±n/a nM |
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| Citation |  Pagé, D; McClory, A; Mischki, T; Schmidt, R; Butterworth, J; St-Onge, S; Labarre, M; Payza, K; Brown, W Novel Dmt-Tic dipeptide analogues as selective delta-opioid receptor antagonists. Bioorg Med Chem Lett10:167-70 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50451122 |
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| n/a |
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| Name | BDBM50451122 |
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| Synonyms: | CHEMBL2115430 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24Br2N2O5 |
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| Mol. Mass. | 556.244 |
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| SMILES | COc1c(Br)cc2C[C@H](N(Cc2c1Br)C(=O)[C@H](N)Cc1c(C)cc(O)cc1C)C(O)=O |
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| Structure | 
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