Compile Data Set for Download or QSAR

Found 1900 hits with Last Name = 'schmidt' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES CC(CN1C[C@H](C)O[C@H](C)C1)Cc1ccc(cc1)C(C)(C)C |r| Show InChI InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	0.00500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in guinea pig whole brain microsomes				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES CC(CN1C[C@H](C)O[C@H](C)C1)Cc1ccc(cc1)C(C)(C)C |r| Show InChI InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	0.0110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in guinea pig liver microsomes				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES CC(CN1C[C@H](C)O[C@H](C)C1)Cc1ccc(cc1)C(C)(C)C |r| Show InChI InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from recombinant guinea pig His6-tagged sigma 1 receptor expressed in Saccharomyces cerevisiae WAO microsomes				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50085050 (CHEMBL152690 | H-Dmt-c [-D-Orn-2-Nal-D-Pro-Gly-]) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C36H44N6O6/c1-21-15-26(43)16-22(2)27(21)19-28(37)33(45)40-29-9-5-13-38-32(44)20-39-35(47)31-10-6-14-42(31)36(48)30(41-34(29)46)18-23-11-12-24-7-3-4-8-25(24)17-23/h3-4,7-8,11-12,15-17,28-31,43H,5-6,9-10,13-14,18-20,37H2,1-2H3,(H,38,44)(H,39,47)(H,40,45)(H,41,46)/t28-,29+,30-,31+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.467	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montr£al Curated by ChEMBL					Assay Description Binding affinity was determined by displacement of [3H]- DSLET at Opioid receptor delta 1 in rat brain membrane homogenates				J Med Chem 43: 551-9 (2000) BindingDB Entry DOI: 10.7270/Q2WQ04H9
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50085050 (CHEMBL152690 | H-Dmt-c [-D-Orn-2-Nal-D-Pro-Gly-]) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C36H44N6O6/c1-21-15-26(43)16-22(2)27(21)19-28(37)33(45)40-29-9-5-13-38-32(44)20-39-35(47)31-10-6-14-42(31)36(48)30(41-34(29)46)18-23-11-12-24-7-3-4-8-25(24)17-23/h3-4,7-8,11-12,15-17,28-31,43H,5-6,9-10,13-14,18-20,37H2,1-2H3,(H,38,44)(H,39,47)(H,40,45)(H,41,46)/t28-,29+,30-,31+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.476	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montr£al Curated by ChEMBL					Assay Description Binding affinity was determined by displacement of [3H]- DAMGO at Opioid receptor mu 1 in rat brain membrane homogenates				J Med Chem 43: 551-9 (2000) BindingDB Entry DOI: 10.7270/Q2WQ04H9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041142 ((S)-2-Amino-N-((5S,8S,16aR)-5-benzyl-4,7,13,16-tet...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O Show InChI InChI=1S/C30H38N6O6/c31-22(16-20-10-12-21(37)13-11-20)27(39)34-23-8-4-14-32-26(38)18-33-29(41)25-9-5-15-36(25)30(42)24(35-28(23)40)17-19-6-2-1-3-7-19/h1-3,6-7,10-13,22-25,37H,4-5,8-9,14-18,31H2,(H,32,38)(H,33,41)(H,34,39)(H,35,40)/t22-,23-,24-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50242666 (CHEMBL4083034) Show SMILES CC(C)(C)c1ccc(CCCN2CCCCC2)cc1 Show InChI InChI=1S/C18H29N/c1-18(2,3)17-11-9-16(10-12-17)8-7-15-19-13-5-4-6-14-19/h9-12H,4-8,13-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from recombinant human sigma 1 receptor expressed in baculovirus infected Sf9 insect cell membranes after 90 min...				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370624 (CHEMBL4169752 | US10954217, Example 00234) Show SMILES C(N1CCc2cc(ccc2C1)N1CCOCC1)c1ccccc1 Show InChI InChI=1S/C20H24N2O/c1-2-4-17(5-3-1)15-21-9-8-18-14-20(7-6-19(18)16-21)22-10-12-23-13-11-22/h1-7,14H,8-13,15-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041146 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-[(5S,8R,16aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O Show InChI InChI=1S/C32H39N7O6/c33-23(15-19-9-11-21(40)12-10-19)29(42)37-25-7-3-13-34-28(41)18-36-31(44)27-8-4-14-39(27)32(45)26(38-30(25)43)16-20-17-35-24-6-2-1-5-22(20)24/h1-2,5-6,9-12,17,23,25-27,35,40H,3-4,7-8,13-16,18,33H2,(H,34,41)(H,36,44)(H,37,42)(H,38,43)/t23-,25+,26-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50242668 (CHEMBL4071509) Show SMILES C[C@@H]1CN(CCCc2ccc(cc2)C(C)(C)C)C[C@@H](C)O1 |r| Show InChI InChI=1S/C19H31NO/c1-15-13-20(14-16(2)21-15)12-6-7-17-8-10-18(11-9-17)19(3,4)5/h8-11,15-16H,6-7,12-14H2,1-5H3/t15-,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from recombinant human sigma 1 receptor expressed in baculovirus infected Sf9 insect cell membranes after 90 min...				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001465 ((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50242670 (CHEMBL4090823) Show SMILES CC(C)(C)c1ccc(CCCN2CCOCC2)cc1 Show InChI InChI=1S/C17H27NO/c1-17(2,3)16-8-6-15(7-9-16)5-4-10-18-11-13-19-14-12-18/h6-9H,4-5,10-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from recombinant human sigma 1 receptor expressed in baculovirus infected Sf9 insect cell membranes after 90 min...				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370623 (CHEMBL4165863 | US10954217, Example 00237) Show SMILES O=C(OCc1ccccc1)N1CCc2ccc(cc2C1)N1CCN(CC1)C1CCCC1 Show InChI InChI=1S/C26H33N3O2/c30-26(31-20-21-6-2-1-3-7-21)29-13-12-22-10-11-25(18-23(22)19-29)28-16-14-27(15-17-28)24-8-4-5-9-24/h1-3,6-7,10-11,18,24H,4-5,8-9,12-17,19-20H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041148 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,13aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C32H37N5O5/c33-25(18-20-10-13-24(38)14-11-20)29(39)35-26-7-3-15-34-31(41)28-8-4-16-37(28)32(42)27(36-30(26)40)19-21-9-12-22-5-1-2-6-23(22)17-21/h1-2,5-6,9-14,17,25-28,38H,3-4,7-8,15-16,18-19,33H2,(H,34,41)(H,35,39)(H,36,40)/t25-,26-,27-,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50041144 ((S)-2-Amino-N-((5S,8S)-5-benzyl-4,7,13,16-tetraoxo...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C37H39N5O5/c38-30(19-26-15-17-29(43)18-16-26)37(47)42-23-28-14-8-7-13-27(28)22-33(42)36(46)41-32(21-25-11-5-2-6-12-25)35(45)40-31(34(39)44)20-24-9-3-1-4-10-24/h1-18,30-33,43H,19-23,38H2,(H2,39,44)(H,40,45)(H,41,46)/t30-,31-,32-,33-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041144 ((S)-2-Amino-N-((5S,8S)-5-benzyl-4,7,13,16-tetraoxo...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C37H39N5O5/c38-30(19-26-15-17-29(43)18-16-26)37(47)42-23-28-14-8-7-13-27(28)22-33(42)36(46)41-32(21-25-11-5-2-6-12-25)35(45)40-31(34(39)44)20-24-9-3-1-4-10-24/h1-18,30-33,43H,19-23,38H2,(H2,39,44)(H,40,45)(H,41,46)/t30-,31-,32-,33-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041141 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8R,16aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2cccc3ccccc23)NC1=O Show InChI InChI=1S/C34H40N6O6/c35-26(18-21-12-14-24(41)15-13-21)31(43)38-27-10-4-16-36-30(42)20-37-33(45)29-11-5-17-40(29)34(46)28(39-32(27)44)19-23-8-3-7-22-6-1-2-9-25(22)23/h1-3,6-9,12-15,26-29,41H,4-5,10-11,16-20,35H2,(H,36,42)(H,37,45)(H,38,43)(H,39,44)/t26-,27+,28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370680 (CHEMBL4172703) Show SMILES [H][C@@]12C[C@@]([H])(N(CC1)C(=O)OCc1ccccc1)c1cc(ccc21)N1CCN(CC1)C1CCCC1 |r| Show InChI InChI=1S/C28H35N3O2/c32-28(33-20-21-6-2-1-3-7-21)31-13-12-22-18-27(31)26-19-24(10-11-25(22)26)30-16-14-29(15-17-30)23-8-4-5-9-23/h1-3,6-7,10-11,19,22-23,27H,4-5,8-9,12-18,20H2/t22-,27+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50370571 (CHEMBL4160064 | US10954217, Example 00236) Show SMILES COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)CCc2c1 Show InChI InChI=1S/C23H23NO/c1-25-23-9-5-8-19(15-23)20-10-11-22-17-24(13-12-21(22)14-20)16-18-6-3-2-4-7-18/h2-11,14-15H,12-13,16-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D4 expressed in stable HEK cells after 90 mins by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50041145 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S)-5-naph...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(=O)CNC2=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C30H38N6O6/c31-22(16-20-10-12-21(37)13-11-20)27(39)34-23-8-4-14-32-26(38)18-33-29(41)25-9-5-15-36(25)30(42)24(35-28(23)40)17-19-6-2-1-3-7-19/h1-3,6-7,10-13,22-25,37H,4-5,8-9,14-18,31H2,(H,32,38)(H,33,41)(H,34,39)(H,35,40)/t22-,23+,24-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041145 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S)-5-naph...) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(=O)CNC2=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C30H38N6O6/c31-22(16-20-10-12-21(37)13-11-20)27(39)34-23-8-4-14-32-26(38)18-33-29(41)25-9-5-15-36(25)30(42)24(35-28(23)40)17-19-6-2-1-3-7-19/h1-3,6-7,10-13,22-25,37H,4-5,8-9,14-18,31H2,(H,32,38)(H,33,41)(H,34,39)(H,35,40)/t22-,23+,24-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370603 (CHEMBL4167315 | US10954217, Example 00225) Show SMILES COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)Cc2c1 Show InChI InChI=1S/C22H21NO/c1-24-22-9-5-8-18(13-22)19-10-11-20-15-23(16-21(20)12-19)14-17-6-3-2-4-7-17/h2-13H,14-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370571 (CHEMBL4160064 | US10954217, Example 00236) Show SMILES COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)CCc2c1 Show InChI InChI=1S/C23H23NO/c1-25-23-9-5-8-19(15-23)20-10-11-22-17-24(13-12-21(22)14-20)16-18-6-3-2-4-7-18/h2-11,14-15H,12-13,16-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50242671 (CHEMBL4101014) Show SMILES CC1CCN(CCCc2ccc(cc2)C(C)(C)C)CC1 Show InChI InChI=1S/C19H31N/c1-16-11-14-20(15-12-16)13-5-6-17-7-9-18(10-8-17)19(2,3)4/h7-10,16H,5-6,11-15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from recombinant human sigma 1 receptor expressed in baculovirus infected Sf9 insect cell membranes after 90 min...				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041143 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,16aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C34H40N6O6/c35-26(18-21-10-13-25(41)14-11-21)31(43)38-27-7-3-15-36-30(42)20-37-33(45)29-8-4-16-40(29)34(46)28(39-32(27)44)19-22-9-12-23-5-1-2-6-24(23)17-22/h1-2,5-6,9-14,17,26-29,41H,3-4,7-8,15-16,18-20,35H2,(H,36,42)(H,37,45)(H,38,43)(H,39,44)/t26-,27-,28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370662 (CHEMBL4161503 | US10954217, Example 00224) Show SMILES C(N1Cc2ccc(cc2C1)N1CCOCC1)c1ccccc1 Show InChI InChI=1S/C19H22N2O/c1-2-4-16(5-3-1)13-20-14-17-6-7-19(12-18(17)15-20)21-8-10-22-11-9-21/h1-7,12H,8-11,13-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370661 (CHEMBL4175187 | US10954217, Example 00253) Show SMILES C(N1CCCc2cc(ccc2C1)N1CCOCC1)c1ccccc1 Show InChI InChI=1S/C21H26N2O/c1-2-5-18(6-3-1)16-22-10-4-7-19-15-21(9-8-20(19)17-22)23-11-13-24-14-12-23/h1-3,5-6,8-9,15H,4,7,10-14,16-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041149 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5R,8R,15aS)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCNC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C33H38N6O6/c34-25(17-20-8-11-24(40)12-9-20)30(42)37-26-13-14-35-29(41)19-36-32(44)28-6-3-15-39(28)33(45)27(38-31(26)43)18-21-7-10-22-4-1-2-5-23(22)16-21/h1-2,4-5,7-12,16,25-28,40H,3,6,13-15,17-19,34H2,(H,35,41)(H,36,44)(H,37,42)(H,38,43)/t25-,26+,27+,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370518 (CHEMBL4176474 | US10954217, Example 00229) Show SMILES O=C(OCc1ccccc1)N1Cc2ccc(cc2C1)N1CCN(CC1)C1CCCC1 Show InChI InChI=1S/C25H31N3O2/c29-25(30-19-20-6-2-1-3-7-20)28-17-21-10-11-24(16-22(21)18-28)27-14-12-26(13-15-27)23-8-4-5-9-23/h1-3,6-7,10-11,16,23H,4-5,8-9,12-15,17-19H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50242669 (CHEMBL4098546) Show SMILES CC1CN(CCCc2ccc(cc2)C(C)(C)C)CC(C)O1 Show InChI InChI=1S/C19H31NO/c1-15-13-20(14-16(2)21-15)12-6-7-17-8-10-18(11-9-17)19(3,4)5/h8-11,15-16H,6-7,12-14H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from recombinant human sigma 1 receptor expressed in baculovirus infected Sf9 insect cell membranes after 90 min...				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001465 ((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50041146 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-[(5S,8R,16aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O Show InChI InChI=1S/C32H39N7O6/c33-23(15-19-9-11-21(40)12-10-19)29(42)37-25-7-3-13-34-28(41)18-36-31(44)27-8-4-14-39(27)32(45)26(38-30(25)43)16-20-17-35-24-6-2-1-5-22(20)24/h1-2,5-6,9-12,17,23,25-27,35,40H,3-4,7-8,13-16,18,33H2,(H,34,41)(H,36,44)(H,37,42)(H,38,43)/t23-,25+,26-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370930 (CHEMBL4167368) Show SMILES [H][C@@]12C[C@@]([H])(N(Cc3ccccc3)CC1)c1ccc(cc21)-c1cccc(OC)c1 |r| Show InChI InChI=1S/C25H25NO/c1-27-22-9-5-8-19(14-22)20-10-11-23-24(15-20)21-12-13-26(25(23)16-21)17-18-6-3-2-4-7-18/h2-11,14-15,21,25H,12-13,16-17H2,1H3/t21-,25+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50041142 ((S)-2-Amino-N-((5S,8S,16aR)-5-benzyl-4,7,13,16-tet...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O Show InChI InChI=1S/C30H38N6O6/c31-22(16-20-10-12-21(37)13-11-20)27(39)34-23-8-4-14-32-26(38)18-33-29(41)25-9-5-15-36(25)30(42)24(35-28(23)40)17-19-6-2-1-3-7-19/h1-3,6-7,10-13,22-25,37H,4-5,8-9,14-18,31H2,(H,32,38)(H,33,41)(H,34,39)(H,35,40)/t22-,23-,24-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370628 (CHEMBL4166276 | US10954217, Example 00262) Show SMILES O=C(OCc1ccccc1)N1CCCc2ccc(cc2C1)N1CCN(CC1)C1CCCC1 Show InChI InChI=1S/C27H35N3O2/c31-27(32-21-22-7-2-1-3-8-22)30-14-6-9-23-12-13-26(19-24(23)20-30)29-17-15-28(16-18-29)25-10-4-5-11-25/h1-3,7-8,12-13,19,25H,4-6,9-11,14-18,20-21H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50242671 (CHEMBL4101014) Show SMILES CC1CCN(CCCc2ccc(cc2)C(C)(C)C)CC1 Show InChI InChI=1S/C19H31N/c1-16-11-14-20(15-12-16)13-5-6-17-7-9-18(10-8-17)19(2,3)4/h7-10,16H,5-6,11-15H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-ditolylguanidine from recombinant rat sigma 2 receptor expressed in rat PC12 cell membranes after 90 mins in presence of sig...				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50543309 (CHEMBL4647090) Show SMILES OC1COCCC1NC1CCN(CC1)c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C16H22F3N3O2/c17-16(18,19)11-1-2-15(20-9-11)22-6-3-12(4-7-22)21-13-5-8-24-10-14(13)23/h1-2,9,12-14,21,23H,3-8,10H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-DTG from recombinant sigma 2 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5 hrs by ...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50041147 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,17aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C35H42N6O6/c36-27(19-22-11-14-26(42)15-12-22)32(44)39-28-8-3-4-16-37-31(43)21-38-34(46)30-9-5-17-41(30)35(47)29(40-33(28)45)20-23-10-13-24-6-1-2-7-25(24)18-23/h1-2,6-7,10-15,18,27-30,42H,3-5,8-9,16-17,19-21,36H2,(H,37,43)(H,38,46)(H,39,44)(H,40,45)/t27-,28-,29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptors by displacement of [3H]-DAMGO from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50041143 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,16aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C34H40N6O6/c35-26(18-21-10-13-25(41)14-11-21)31(43)38-27-7-3-15-36-30(42)20-37-33(45)29-8-4-16-40(29)34(46)28(39-32(27)44)19-22-9-12-23-5-1-2-6-24(23)17-22/h1-2,5-6,9-14,17,26-29,41H,3-4,7-8,15-16,18-20,35H2,(H,36,42)(H,37,45)(H,38,43)(H,39,44)/t26-,27-,28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370622 (CHEMBL4159461) Show SMILES [H][C@@]12C[C@@]([H])(N(Cc3ccccc3)CC1)c1ccc(cc21)N1CCOCC1 |r| Show InChI InChI=1S/C22H26N2O/c1-2-4-17(5-3-1)16-24-9-8-18-14-22(24)20-7-6-19(15-21(18)20)23-10-12-25-13-11-23/h1-7,15,18,22H,8-14,16H2/t18-,22+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES CC(CN1C[C@H](C)O[C@H](C)C1)Cc1ccc(cc1)C(C)(C)C |r| Show InChI InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of (+)-[3H]-pentazocine from recombinant human sigma 1 receptor expressed in baculovirus infected Sf9 insect cell membranes after 90 min...				Bioorg Med Chem Lett 27: 2912-2919 (2017) Article DOI: 10.1016/j.bmcl.2017.04.088 BindingDB Entry DOI: 10.7270/Q2154KF1
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370621 (CHEMBL4168236) Show SMILES [H][C@@]12C[C@@]([H])(N(CC1)C(=O)OCc1ccccc1)c1cc(ccc21)N1CCN(CC(C)=C)CC1 |r| Show InChI InChI=1S/C27H33N3O2/c1-20(2)18-28-12-14-29(15-13-28)23-8-9-24-22-10-11-30(26(16-22)25(24)17-23)27(31)32-19-21-6-4-3-5-7-21/h3-9,17,22,26H,1,10-16,18-19H2,2H3/t22-,26+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50543309 (CHEMBL4647090) Show SMILES OC1COCCC1NC1CCN(CC1)c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C16H22F3N3O2/c17-16(18,19)11-1-2-15(20-9-11)22-6-3-12(4-7-22)21-13-5-8-24-10-14(13)23/h1-2,9,12-14,21,23H,3-8,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370619 (CHEMBL4162416 | US10954217, Example 00264) Show SMILES CC(=C)CN1CCN(CC1)c1ccc2CCCN(Cc2c1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C26H33N3O2/c1-21(2)18-27-13-15-28(16-14-27)25-11-10-23-9-6-12-29(19-24(23)17-25)26(30)31-20-22-7-4-3-5-8-22/h3-5,7-8,10-11,17H,1,6,9,12-16,18-20H2,2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50370928 (CHEMBL4170703 | US10954217, Example 00255) Show SMILES COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)CCCc2c1 Show InChI InChI=1S/C24H25NO/c1-26-24-11-5-9-21(16-24)22-12-13-23-18-25(14-6-10-20(23)15-22)17-19-7-3-2-4-8-19/h2-5,7-9,11-13,15-16H,6,10,14,17-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50543307 (CHEMBL4644243) Show SMILES Fc1ccc(CN2CCCN(C2)C(=S)Nc2cc(F)cc(F)c2)cc1 Show InChI InChI=1S/C18H18F3N3S/c19-14-4-2-13(3-5-14)11-23-6-1-7-24(12-23)18(25)22-17-9-15(20)8-16(21)10-17/h2-5,8-10H,1,6-7,11-12H2,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370780 (CHEMBL4164801) Show SMILES [H][C@@]12C[C@@]([H])(N(CC1)C(=O)OCc1ccccc1)c1cc(ccc21)N1CCN(CCC(=O)OCC)CC1 |r| Show InChI InChI=1S/C28H35N3O4/c1-2-34-27(32)11-12-29-14-16-30(17-15-29)23-8-9-24-22-10-13-31(26(18-22)25(24)19-23)28(33)35-20-21-6-4-3-5-7-21/h3-9,19,22,26H,2,10-18,20H2,1H3/t22-,26+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50041141 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8R,16aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2cccc3ccccc23)NC1=O Show InChI InChI=1S/C34H40N6O6/c35-26(18-21-12-14-24(41)15-13-21)31(43)38-27-10-4-16-36-30(42)20-37-33(45)29-11-5-17-40(29)34(46)28(39-32(27)44)19-23-8-3-7-22-6-1-2-9-25(22)23/h1-3,6-9,12-15,26-29,41H,4-5,10-11,16-20,35H2,(H,36,42)(H,37,45)(H,38,43)(H,39,44)/t26-,27+,28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50370625 (CHEMBL4173095 | US10954217, Example 00241) Show SMILES CC(=C)CN1CCN(CC1)c1ccc2CCN(Cc2c1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C25H31N3O2/c1-20(2)17-26-12-14-27(15-13-26)24-9-8-22-10-11-28(18-23(22)16-24)25(29)30-19-21-6-4-3-5-7-21/h3-9,16H,1,10-15,17-19H2,2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting method				Eur J Med Chem 151: 557-567 (2018) Article DOI: 10.1016/j.ejmech.2018.02.024 BindingDB Entry DOI: 10.7270/Q28918FQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50041148 ((S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,13aR)-5...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O Show InChI InChI=1S/C32H37N5O5/c33-25(18-20-10-13-24(38)14-11-20)29(39)35-26-7-3-15-34-31(41)28-8-4-16-37(28)32(42)27(36-30(26)40)19-21-9-12-22-5-1-2-6-23(22)17-21/h1-2,5-6,9-14,17,25-28,38H,3-4,7-8,15-16,18-19,33H2,(H,34,41)(H,35,39)(H,36,40)/t25-,26-,27-,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptors was determined by displacement of [3H]DSLET from rat brain membrane binding site				J Med Chem 37: 1136-44 (1994) BindingDB Entry DOI: 10.7270/Q22Z1650
					More data for this Ligand-Target Pair

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