| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsinogen A |
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| Ligand | BDBM50085342 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_215994 |
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| IC50 | 2200±n/a nM |
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| Citation |  Hayashi, Y; Iijima, K; Katada, J; Kiso, Y Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors. Bioorg Med Chem Lett10:199-201 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsinogen A |
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| Name: | Chymotrypsinogen A |
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| Synonyms: | Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin) |
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| Type: | Serine protease |
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| Mol. Mass.: | 25670.88 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 245 |
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| Sequence: | CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV
TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA
VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM
ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ
TLAAN
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| BDBM50085342 |
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| n/a |
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| Name | BDBM50085342 |
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| Synonyms: | CHEMBL61059 | N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(2,3-dimethoxy-phenyl)-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24ClNO4 |
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| Mol. Mass. | 389.873 |
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| SMILES | COc1cccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)c1OC |
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| Structure | 
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