| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50086663 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_38611 (CHEMBL652294) |
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| Ki | 5300±n/a nM |
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| Citation |  Cecchetti, V; Schiaffella, F; Tabarrini, O; Fravolini, A (1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents. Bioorg Med Chem Lett10:465-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2_CANLF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46593.67 |
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| Organism: | Canis familiaris |
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| Description: | ChEMBL_56504 |
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| Residue: | 415 |
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| Sequence: | MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIAR
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRF
HAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNS
RSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
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|
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| BDBM50086663 |
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| n/a |
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| Name | BDBM50086663 |
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| Synonyms: | 6-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one | CHEMBL143608 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24FN3O3S |
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| Mol. Mass. | 417.497 |
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| SMILES | OC(COc1ccc2SCC(=O)Nc2c1)CN1CCN(CC1)c1ccc(F)cc1 |
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| Structure | 
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