Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAmine oxidase [flavin-containing] B
LigandBDBM50156693
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1921316 (CHEMBL4424161)
IC50>60000±n/a nM
Citation Baek, SC; Kang, MG; Park, JE; Lee, JP; Lee, H; Ryu, HW; Park, CM; Park, D; Cho, ML; Oh, SR; Kim, H Osthenol, a prenylated coumarin, as a monoamine oxidase A inhibitor with high selectivity. Bioorg Med Chem Lett29:839-843 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:Protein
Mol. Mass.:58768.76
Organism:Homo sapiens (Human)
Description:P27338
Residue:520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50156693
n/a
NameBDBM50156693
Synonyms:6-Methoxy-7-hydroxycoumarin | 6-Methylesculetin | 6-O-Methylesculetin | 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one | 7-hydroxy-6-methoxy-2H-chromen-2-one | CHEMBL71851 | scopoletin
TypeSmall organic molecule
Emp. Form.C10H8O4
Mol. Mass.192.1681
SMILESCOc1cc2ccc(=O)oc2cc1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: