| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50084978 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1921315 (CHEMBL4424160) |
|---|
| IC50 | 190±n/a nM |
|---|
| Citation |  Baek, SC; Kang, MG; Park, JE; Lee, JP; Lee, H; Ryu, HW; Park, CM; Park, D; Cho, ML; Oh, SR; Kim, H Osthenol, a prenylated coumarin, as a monoamine oxidase A inhibitor with high selectivity. Bioorg Med Chem Lett29:839-843 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 59689.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21397 |
|---|
| Residue: | 527 |
|---|
| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
|
|
|
|---|
| BDBM50084978 |
|---|
| n/a |
|---|
| Name | BDBM50084978 |
|---|
| Synonyms: | 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one | CHEMBL40919 | Kaempferide | Kaempferol 4'-methyl ether |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H12O6 |
|---|
| Mol. Mass. | 300.2629 |
|---|
| SMILES | COc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
