| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate receptor 3 |
|---|
| Ligand | BDBM50088197 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_90292 (CHEMBL697511) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Pedregal, C; Collado, I; Escribano, A; Ezquerra, J; Domínguez, C; Mateo, AI; Rubio, A; Baker, SR; Goldsworthy, J; Kamboj, RK; Ballyk, BA; Hoo, K; Bleakman, D 4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists. J Med Chem43:1958-68 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glutamate receptor 3 |
|---|
| Name: | Glutamate receptor 3 |
|---|
| Synonyms: | AMPA-selective glutamate receptor 3 | GLUR3 | GLURC | GRIA3 | GRIA3_HUMAN | GluR-3 | GluR-C | GluR-K3 | Glutamate receptor 3 | Glutamate receptor ionotropic AMPA | Glutamate receptor ionotropic, AMPA 3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 101172.14 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_468627 |
|---|
| Residue: | 894 |
|---|
| Sequence: | MARQKKMGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNT
NQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGAL
HTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEA
AVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHS
RGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKN
APLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKM
VQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSASS
ENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKY
GARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS
KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPP
NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVER
MVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTAD
GVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRNAVNL
AVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMM
VALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
|
|
|
|---|
| BDBM50088197 |
|---|
| n/a |
|---|
| Name | BDBM50088197 |
|---|
| Synonyms: | CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-allyl]-pentanedioic acid(LY339295) | LY-339295 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H16ClNO4 |
|---|
| Mol. Mass. | 297.734 |
|---|
| SMILES | N[C@@H](C[C@@H](C\C=C\c1ccc(Cl)cc1)C(O)=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
