Reaction Details |
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Target | Neuropeptide Y receptor type 4 |
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Ligand | BDBM50532420 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1923148 (CHEMBL4426104) |
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IC50 | 69±n/a nM |
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Citation | Liu, M; Mountford, SJ; Richardson, RR; Groenen, M; Holliday, ND; Thompson, PE Optically Pure, Structural, and Fluorescent Analogues of a Dimeric Y4 Receptor Agonist Derived by an Olefin Metathesis Approach. J Med Chem59:6059-69 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Neuropeptide Y receptor type 4 |
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Name: | Neuropeptide Y receptor type 4 |
Synonyms: | NPY-Y4 | NPY4-R | NPY4R | NPY4R_HUMAN | PP1 | PPYR1 | Pancreatic polypeptide receptor 1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 42207.58 |
Organism: | Homo sapiens (Human) |
Description: | NPY-Y4 PPYR1 HUMAN::P50391 |
Residue: | 375 |
Sequence: | MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNL
CLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFI
QCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSIL
ENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRR
LQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHG
NLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTE
VSKGSLRLSGRSNPI
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BDBM50532420 |
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n/a |
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Name | BDBM50532420 |
Synonyms: | CHEMBL4475071 |
Type | Small organic molecule |
Emp. Form. | C80H124N26O16 |
Mol. Mass. | 1706.0052 |
SMILES | CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| |
Structure |
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