| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50532515 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1923200 (CHEMBL4426156) |
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| Ki | 3.2±n/a nM |
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| Citation |  Sun, H; Shi, M; Zhang, W; Zheng, YM; Xu, YZ; Shi, JJ; Liu, T; Gunosewoyo, H; Pang, T; Gao, ZB; Yang, F; Tang, J; Yu, LF Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy. J Med Chem59:6329-43 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50532515 |
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| n/a |
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| Name | BDBM50532515 |
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| Synonyms: | CHEMBL4470605 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18BrClN2O3 |
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| Mol. Mass. | 389.672 |
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| SMILES | Cl.Brc1cccc(OCc2cc(OC[C@@H]3CCCN3)no2)c1 |r| |
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| Structure | 
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