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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50532486
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1923200 (CHEMBL4426156)
Ki 0.300000±n/a nM
Citation Sun, HShi, MZhang, WZheng, YMXu, YZShi, JJLiu, TGunosewoyo, HPang, TGao, ZBYang, FTang, JYu, LF Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy. J Med Chem59:6329-43 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50532486
n/a
NameBDBM50532486
Synonyms:CHEMBL4564992
TypeSmall organic molecule
Emp. Form.C19H27ClN2O3
Mol. Mass.366.882
SMILESCl.CN(CCOc1cc(COc2ccccc2)on1)C1CCCCC1
Structure
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