| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50532518 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1923201 (CHEMBL4426157) |
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| Ki | 15±n/a nM |
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| Citation |  Sun, H; Shi, M; Zhang, W; Zheng, YM; Xu, YZ; Shi, JJ; Liu, T; Gunosewoyo, H; Pang, T; Gao, ZB; Yang, F; Tang, J; Yu, LF Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy. J Med Chem59:6329-43 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20953.88 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5U3Y7 |
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| Residue: | 176 |
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| Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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| BDBM50532518 |
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| n/a |
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| Name | BDBM50532518 |
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| Synonyms: | CHEMBL4440420 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26Cl2N2O3 |
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| Mol. Mass. | 401.327 |
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| SMILES | Cl.CN(CCOc1cc(COc2cccc(Cl)c2)on1)C1CCCCC1 |
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| Structure | 
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