| Reaction Details |
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 | Report a problem with these data |
| Target | Bombesin receptor subtype-3 |
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| Ligand | BDBM50533333 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1925032 (CHEMBL4427988) |
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| EC50 | 7.0±n/a nM |
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| Citation |  Kiyotsuka, Y; Shimada, K; Kobayashi, S; Suzuki, M; Akiu, M; Asano, M; Sogawa, Y; Hara, T; Konishi, M; Abe-Ohya, R; Izumi, M; Nagai, Y; Yoshida, K; Abe, Y; Takamori, H; Takahashi, H Synthesis and biological evaluation of novel imidazol-1-ylacetic acid derivatives as non-brain penetrant bombesin receptor subtype-3 (BRS-3) agonists. Bioorg Med Chem Lett26:4205-10 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bombesin receptor subtype-3 |
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| Name: | Bombesin receptor subtype-3 |
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| Synonyms: | BRS3_MOUSE | Brs3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44239.49 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1445902 |
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| Residue: | 399 |
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| Sequence: | MSQRQSQSPNQTLISITNDTETSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYAGIISV
GILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGC
KVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGGIWIVSMIFAL
PEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLI
ARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYES
YANHSDVPFVIIIFSRVLAFSNSCVNPFALYWLSKTFQQHFKAQLCCLKAEQPEPPLGDI
PLNNLTVMGRVPATGSAHVSEISVTLFSGSSAKKGEDKV
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| BDBM50533333 |
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| n/a |
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| Name | BDBM50533333 |
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| Synonyms: | CHEMBL4464287 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34FN3O4S |
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| Mol. Mass. | 515.64 |
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| SMILES | COC(=O)c1c(F)cccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2CCNS(C)(=O)=O)cc1 |
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| Structure | 
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