| Reaction Details |
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 | Report a problem with these data |
| Target | B2 bradykinin receptor |
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| Ligand | BDBM50089308 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_40428 (CHEMBL652643) |
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| Ki | 0.08±n/a nM |
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| Citation |  Amblard, M; Bedos, P; Olivier, C; Daffix, I; Luccarini, JM; Dodey, P; Pruneau, D; Paquet, JL; Martinez, J Synthesis and biological evaluation of bradykinin B(1)/B(2) and selective B(1) receptor antagonists. J Med Chem43:2382-6 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| B2 bradykinin receptor |
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| Name: | B2 bradykinin receptor |
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| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44467.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
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| Residue: | 391 |
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| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
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| BDBM50089308 |
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| n/a |
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| Name | BDBM50089308 |
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| Synonyms: | CHEMBL412349 | H-DArg-Arg-Pro-Hyp-Gly-Thi-Ser-DTic-Oic-Arg-OH( HOE140) |
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| Type | Small organic molecule |
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| Emp. Form. | C59H83N19O13S |
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| Mol. Mass. | 1298.475 |
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| SMILES | NC(CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CC(O)C[C@H]1C(=O)NCC(=O)NC(Cc1cccs1)C(=O)N[C@@H](CO)C(=O)N1Cc2ccccc2CC1C(=O)N1C(Cc2ccccc12)C(=O)NC(CCCNC(N)=N)C(O)=O |
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| Structure | 
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