| Reaction Details |
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 | Report a problem with these data |
| Target | N-methyl-D-aspartate receptor |
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| Ligand | BDBM50079387 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_141415 (CHEMBL751709) |
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| IC50 | 11300±n/a nM |
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| Citation |  Pabel, J; Höfner, G; Wanner, KT Synthesis and resolution of racemic eliprodil and evaluation of the enantiomers of eliprodil as NMDA receptor antagonists. Bioorg Med Chem Lett10:1377-80 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| N-methyl-D-aspartate receptor |
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| Name: | N-methyl-D-aspartate receptor |
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| Synonyms: | Glutamate (NMDA) receptor subunit zeta 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27123.62 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_141416 |
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| Residue: | 243 |
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| Sequence: | TAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSD
DHEGRAARKRLETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAA
TVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVA
QAVHELLEKENITEPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNKDGDRKFA
NYS
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| BDBM50079387 |
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| n/a |
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| Name | BDBM50079387 |
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| Synonyms: | 1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanol | CHEMBL28564 | Eliprodil |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23ClFNO |
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| Mol. Mass. | 347.854 |
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| SMILES | OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 |
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| Structure | 
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