| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1A1 |
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| Ligand | BDBM50081709 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1931142 (CHEMBL4434393) |
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| IC50 | 4.8±n/a nM |
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| Citation |  Zhao, L; Sun, N; Tian, L; Zhao, S; Sun, B; Sun, Y; Zhao, D Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current research. Bioorg Med Chem Lett29:2016-2024 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1A1 |
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| Name: | Cytochrome P450 1A1 |
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| Synonyms: | CP1A1_HUMAN | CYP1A1 | CYPIA1 | Cytochrome P450 1A | Cytochrome P450 1A1 | Cytochrome P450 1A1 (CYP1A1) | P450 form 6 | P450-C | P450-P1 |
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| Type: | Protein |
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| Mol. Mass.: | 58177.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04798 |
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| Residue: | 512 |
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| Sequence: | MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPH
LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQS
MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAG
PGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPIL
RYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANV
QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS
DRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKL
WVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEF
SVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS
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| BDBM50081709 |
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| n/a |
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| Name | BDBM50081709 |
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| Synonyms: | CHEMBL3422257 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18O5 |
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| Mol. Mass. | 362.3753 |
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| SMILES | COc1ccc(OC)c2c1c(OC)cc1c2oc(cc1=O)-c1ccccc1 |
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| Structure | 
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