| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase catalytic subunit |
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| Ligand | BDBM50091982 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157582 |
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| IC50 | >100000±n/a nM |
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| Citation |  Vaillancourt, VA; Cudahy, MM; Staley, SA; Brideau, RJ; Conrad, SJ; Knechtel, ML; Oien, NL; Wieber, JL; Yagi, Y; Wathen, MW Naphthalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase. Bioorg Med Chem Lett10:2079-81 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase catalytic subunit |
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| Name: | DNA polymerase catalytic subunit |
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| Synonyms: | DPOL_HHV6U | Human herpesvirus 6 DNA polymerase | U38 | XILF0 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 115827.55 |
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| Organism: | Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human Blymphotropic virus) |
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| Description: | ChEMBL_157582 |
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| Residue: | 1012 |
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| Sequence: | MDSVSFFNPYLEANRLKKKSRSSYIRILPRGIMHDGAAGLIKDVCDSEPRMFYRDRQYLL
SKEMTWPSLDIARSKDYDHMRMKFHIYDAVETLMFTDSIENLPFQYRHFVIPSGTVIRMF
GRTEDGEKICVNVFGQEQYFYCECVDGRSLKATINNLMLTGEVKMSCSFVIEPADKLSLY
GYNANTVVNLFKVSFGNFYVSQRIGKILQNEGFVVYEIDVDVLTRFFVDNGFLSFGWYNV
KKYIPQDMGKGSNLEVEINCHVSDLVSLEDVNWPLYGCWSFDIECLGQNGNFPDAENLGD
IVIQISVISFDTEGDRDERHLFTLGTCEKIDGVHIYEFASEFELLLGFFIFLRIESPEFI
TGYNINNFDLKYLCIRMDKIYHYDIGCFSKLKNGKIGISVPHEQYRKGFLQAQTKVFTSG
VLYLDMYPVYSSKITAQNYKLDTIAKICLQQEKEQLSYKEIPKKFISGPSGRAVVGKYCL
QDSVLVVRLFKQINYHFEVAEVARLAHVTARCVVFEGQQKKIFPCILTEAKRRNMILPSM
VSSHNRQGIGYKGATVLEPKTGYYAVPTVVFDFQSLYPSIMMAHNLCYSTLVLDERQIAG
LSESDILTVKLGDETHRFVKPCIRESVLGSLLKDWLAKRREVKAEMQNCSDPMMKLLLDK
KQLALKTTCNSVYGVTGAAHGLLPCVAIAASVTCLGREMLCSTVDYVNSKMQSEQFFCEE
FGLTSSDFTGDLEVEVIYGDTDSIFMSVRNMVNQSLRRIAPMIAKHITDRLFKSPIKLEF
EKILCPLILICKKRYIGRQDDSLLIFKGVDLVRKTSCDFVKGVVKDIVDLLFFDEEVQTA
AVEFSHMTQTQLREQGVPVGIHKILRRLCEAREELFQNRADVRHLMLSSVLSKEMAAYKQ
PNLAHLSVIRRLAQRKEEIPNVGDRIMYVLIAPSIGNKQTHNYELAEDPNYVIEHKIPIH
AEKYFDQIIKAVTNAISPIFPKTDIKKEKLLLYLLPMKVYLDETFSAIAEVM
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| BDBM50091982 |
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| n/a |
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| Name | BDBM50091982 |
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| Synonyms: | 3-Hydroxy-naphthalene-2-carboxylic acid [2-(4-chloro-phenyl)-ethyl]-amide | CHEMBL65408 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16ClNO2 |
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| Mol. Mass. | 325.789 |
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| SMILES | Oc1cc2ccccc2cc1C(=O)NCCc1ccc(Cl)cc1 |
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| Structure | 
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