| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50093063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212696 |
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| IC50 | >2500±n/a nM |
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| Citation |  Semple, JE; Levy, OE; Minami, NK; Owens, TD; Siev, DV Novel, potent and selective chimeric FXa inhibitors featuring hydrophobic P1-ketoamide moieties. Bioorg Med Chem Lett10:2305-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50093063 |
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| n/a |
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| Name | BDBM50093063 |
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| Synonyms: | (R)-5-Guanidino-2-phenylmethanesulfonylamino-pentanoic acid [((S)-1-cyclohexylmethyl-2-oxo-2-phenethylcarbamoyl-ethylcarbamoyl)-methyl]-methyl-amide | CHEMBL74955 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H49N7O6S |
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| Mol. Mass. | 683.861 |
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| SMILES | CN(CC(=O)N[C@@H](CC1CCCCC1)C(=O)C(=O)NCCc1ccccc1)C(=O)[C@@H](CCCNC(N)=N)NS(=O)(=O)Cc1ccccc1 |
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| Structure | 
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