| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50093225 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_86906 |
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| Ki | 2.1±n/a nM |
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| Citation |  Stark, H; Ligneau, X; Sadek, B; Ganellin, CR; Arrang, JM; Schwartz, JC; Schunack, W Analogues and derivatives of ciproxifan, a novel prototype for generating potent histamine H3-receptor antagonists. Bioorg Med Chem Lett10:2379-82 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50093225 |
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| n/a |
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| Name | BDBM50093225 |
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| Synonyms: | CHEMBL76440 | Cyclopropyl-{4-[2-(1H-imidazol-4-yl)-ethoxy]-phenyl}-methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16N2O2 |
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| Mol. Mass. | 256.2997 |
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| SMILES | O=C(C1CC1)c1ccc(OCCc2cnc[nH]2)cc1 |
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| Structure | 
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