| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 8 |
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| Ligand | BDBM50537502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1936429 (CHEMBL4482188) |
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| IC50 | 6500±n/a nM |
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| Citation |  Li, X; Qiao, Y; Wang, X; Ma, R; Li, T; Zhang, Y; Borris, RP Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3. J Nat Prod82:832-839 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 8 |
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| Name: | Solute carrier family 22 member 8 |
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| Synonyms: | OAT3 | Organic anion transporter 3 | S22A8_HUMAN | SLC22A8 | hOAT3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59870.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1486920 |
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| Residue: | 542 |
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| Sequence: | MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGPW
VLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEPCLDGWVYNSTKDSIVTEWDLVCNSNK
LKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFR
FLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQL
TVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLN
LQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQI
IFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKG
CLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGI
TALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRIPLQPHGPGLG
SS
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| BDBM50537502 |
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| n/a |
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| Name | BDBM50537502 |
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| Synonyms: | CHEMBL38650 | NSC-220968 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18O2 |
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| Mol. Mass. | 266.3343 |
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| SMILES | Cc1c(O)ccc-2c1CCc1cc(O)c(C)c(C=C)c-21 |
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| Structure | 
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