| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
|---|
| Ligand | BDBM50093647 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_143676 (CHEMBL857689) |
|---|
| IC50 | 0.5±n/a nM |
|---|
| Citation |  Norman, MH; Chen, N; Chen, Z; Fotsch, C; Hale, C; Han, N; Hurt, R; Jenkins, T; Kincaid, J; Liu, L; Lu, Y; Moreno, O; Santora, VJ; Sonnenberg, JD; Karbon, W Structure-activity relationships of a series of pyrrolo[3,2-d]pyrimidine derivatives and related compounds as neuropeptide Y5 receptor antagonists. J Med Chem43:4288-312 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 5 |
|---|
| Name: | Neuropeptide Y receptor type 5 |
|---|
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 50746.64 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q15761 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
|
|
|
|---|
| BDBM50093647 |
|---|
| n/a |
|---|
| Name | BDBM50093647 |
|---|
| Synonyms: | 2-Methyl-6-(5-methyl-furan-2-yl)-4-piperidin-1-yl-5H-pyrrolo[3,2-d]pyrimidine | CHEMBL343318 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H20N4O |
|---|
| Mol. Mass. | 296.3669 |
|---|
| SMILES | Cc1ccc(o1)-c1cc2nc(C)nc(N3CCCCC3)c2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
