| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM50081701 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1972213 (CHEMBL4605031) |
|---|
| EC50 | 9.8±n/a nM |
|---|
| Citation |  Sherwood, AM; Halberstadt, AL; Klein, AK; McCorvy, JD; Kaylo, KW; Kargbo, RB; Meisenheimer, P Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin. J Nat Prod83:461-467 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52843.00 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P35363 |
|---|
| Residue: | 471 |
|---|
| Sequence: | MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYK
SSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
|
|
|
|---|
| BDBM50081701 |
|---|
| n/a |
|---|
| Name | BDBM50081701 |
|---|
| Synonyms: | 3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydroxy-N,N-dimethyltryptamine | CHEMBL65547 | N,N-dimethyl-4-hydroxytryptamine | Psilocin | US11427604, Compound (I-45) | US11453689, Compound Psilocin | US11591353, Compound I-45 | US11597738, Example 3 | US11642336, Compound Psilocin | US20240051978, Compound Psilocin |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H16N2O |
|---|
| Mol. Mass. | 204.2682 |
|---|
| SMILES | CN(C)CCc1c[nH]c2cccc(O)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
