| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-9 |
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| Ligand | BDBM50538185 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1972391 (CHEMBL4605209) |
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| IC50 | 90±n/a nM |
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| Citation |  Bhattarai, D; Lee, MJ; Baek, A; Yeo, IJ; Miller, Z; Baek, YM; Lee, S; Kim, DE; Hong, JT; Kim, KB LMP2 Inhibitors as a Potential Treatment for Alzheimer's Disease. J Med Chem63:3763-3783 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-9 |
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| Name: | Proteasome subunit beta type-9 |
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| Synonyms: | LMP2 | Low molecular mass protein 2 | Macropain chain 7 | Multicatalytic endopeptidase complex chain 7 | PSB9_HUMAN | PSMB6i | PSMB9 | Proteasome chain 7 | Proteasome subunit beta-1i | RING12 | Really interesting new gene 12 protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 23256.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_106197 |
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| Residue: | 219 |
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| Sequence: | MLRAGAPTGDLPRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHER
IYCALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMV
AGWDQREGGQVYGTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIA
LAMSRDGSSGGVIYLVTITAAGVDHRVILGNELPKFYDE
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| BDBM50538185 |
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| n/a |
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| Name | BDBM50538185 |
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| Synonyms: | CHEMBL4638653 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H40N6O6 |
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| Mol. Mass. | 628.718 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)c1cnccn1)C(=O)[C@@]1(C)CO1 |r| |
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| Structure | 
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