| Reaction Details |
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 | Report a problem with these data |
| Target | Nonstructural protein 3 |
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| Ligand | BDBM50538478 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1972915 (CHEMBL4605733) |
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| Ki | 11500±n/a nM |
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| Citation |  Pach, S; Sarter, TM; Yousef, R; Schaller, D; Bergemann, S; Arkona, C; Rademann, J; Nitsche, C; Wolber, G Catching a Moving Target: Comparative Modeling of Flaviviral NS2B-NS3 Reveals Small Molecule Zika Protease Inhibitors. ACS Med Chem Lett11:514-520 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Nonstructural protein 3 |
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| Name: | Nonstructural protein 3 |
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| Synonyms: | Genome polyprotein | NS3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 7653.58 |
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| Organism: | Zika virus |
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| Description: | ChEMBL_119671 |
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| Residue: | 66 |
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| Sequence: | AETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMK
RGDLPV
|
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|
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| BDBM50538478 |
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| n/a |
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| Name | BDBM50538478 |
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| Synonyms: | CHEMBL4634219 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30N2O5 |
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| Mol. Mass. | 366.4519 |
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| SMILES | COc1cc(CN2CC(O)C2)ccc1OCC(O)CN1CCC(O)CC1 |
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| Structure | 
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